SCHEMBL496672

SCHEMBL496672

c1ccc(N2c3ccccc3Cc3ccccc32)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.70
ADRA2A P08913 2/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53
GAA P10253 4/20 0.46
PKM P14618 1/20 0.46
TLR9 Q9NR96 1/20 0.46
ALDH1A1 P00352 3/20 0.41
CES2 O00748 1/20 0.41
BCHE P06276 1/20 0.41
CES1 P23141 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
SLC6A2 P23975 3/20 0.41
MGLL Q99685 1/20 0.39
GFER P55789 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TNKS O95271 1/20 0.38
HTR1A P08908 1/20 0.37
DRD2 P14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30420919 1.00 HPGD (0.70) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL17951467 0.98 HPGD (0.68) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL6123772 0.93 HPGD (0.61) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL6123767 0.92 HPGD (0.61) HPGDADRA2AADRA2BADRA2CGAA
Perchlorate SCHEMBL29678106 0.88 HPGD (0.58) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL31539481 0.87 HPGD (0.56) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL2761349 0.87 HPGD (0.56) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL6123811 0.87 HPGD (0.56) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL17171659 0.87 HPGD (0.56) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL12190840 0.86 HPGD (0.55) HPGDADRA2AADRA2BADRA2CGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684998-A Sandwich structure pressure color-changing film based on double-tricyclic aromatic alkene and preparation method and application thereof 中山大学 2025-03-25 CN claimed
CN-115806488-A Method for ring-opening allylation of cycloalkanol 南京工业大学 2023-03-17 CN claimed
US-20110132439-A1 FULLERENE COMPOUNDS FOR SOLAR CELLS AND PHOTODETECTORS University of Washington Center for Commercialization (US) 2011-06-09 US claimed
US-12325721-B2 Organic compound, application thereof, and organic electroluminescent device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-06-10 US disclosed
CN-119684998-A Sandwich structure pressure color-changing film based on double-tricyclic aromatic alkene and preparation method and application thereof 中山大学 2025-03-25 CN disclosed
US-11912712-B2 Organic electroluminescent element having an organic compound BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) 2024-02-27 US disclosed
CN-117164645-A Method for synthesizing thioglycoside by DDQ-mediated glycosyl mercaptan and xanthene derivative through one-pot method 江西师范大学 2023-12-05 CN disclosed
US-20230299242-A1 LIGHT EMITTING DEVICES AND USES THEREOF IN DISPLAYS Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-09-21 US disclosed
US-20230286992-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) 2023-09-14 US disclosed
CN-113122240-B Main and guest doped luminescent material taking iodo-carbazole derivative as main body and preparation and application methods thereof 西北工业大学 2023-08-29 CN disclosed
US-11706972-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
WO-1989006226-A1 SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR QUEST SYSTEMS, INC. (US) 1989-07-13 WO disclosed
EP-0275260-A1 METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES. QUEST SYSTEMS INC (US) 1988-07-27 EP disclosed
WO-1988000695-A1 METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES QUEST SYSTEMS, INC. (US) 1988-01-28 WO disclosed
EP-0035530-B1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-23 EP disclosed
EP-0035530-A4 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET. MINNESOTA MINING & MFG (US) 1982-07-30 EP disclosed
US-4291114-A COMPRISING A PHOTOPOLYMERIZABLE LAYER OF A MONOMER AND A CATIONIC PROMOTER ON AN OLEOPHILIC SURFACE OF A COVERING MINNESOTA MINING AND MANUFACTURING CO. (US) 1981-09-22 US disclosed
EP-0035530-A1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET. MINNESOTA MINING & MFG (US) 1981-09-16 EP disclosed
WO-1981000627-A1 IMAGEABLE,COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING & MFG (US) 1981-03-05 WO disclosed
US-4069054-A Photopolymerizable composition containing a sensitized aromatic sulfonium compound and a cationacally polymerizable monomer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706972-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP HPGD 3627/4885ADRA2A 1218/4885ADRA2B 1370/4885
US-20230286992-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO1A2, SLCO2A1 HPGD 4027/4885ADRA2A 3419/4885ADRA2B 3668/4885
US-11912712-B2 Organic electroluminescent element having an organic compound SLCO4C1, SLCO1A2, SLCO2A1 HPGD 4284/4885ADRA2A 3480/4885ADRA2B 3751/4885
US-20110132439-A1 FULLERENE COMPOUNDS FOR SOLAR CELLS AND PHOTODETECTORS XPA, SUN2, CRY2 HPGD 2304/4885ADRA2A 3663/4885ADRA2B 4398/4885
US-12325721-B2 Organic compound, application thereof, and organic electroluminescent device CHRM1, CHRM2, L1CAM HPGD 2860/4885ADRA2A 1905/4885ADRA2B 1597/4885
US-20230299242-A1 LIGHT EMITTING DEVICES AND USES THEREOF IN DISPLAYS ALDH1A2, CRY1, ALDH1A3 HPGD 915/4885ADRA2A 3215/4885ADRA2B 2656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.