SCHEMBL3697372

SCHEMBL3697372

O=S(=O)(O)c1cc(Nc2nc(Cl)nc(Cl)n2)c2c(O)c(N=Nc3ccccc3)c(S(=O)(=O)O)cc2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FUT8 Q9BYC5 1/20 0.73
ENPP2 Q13822 7/20 0.56
PRMT1 Q99873 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 1/20 0.47
MAPK1 P28482 1/20 0.47
DNASE1L3 Q13609 1/20 0.47
PHLPP2 Q6ZVD8 2/20 0.46
CARM1 Q86X55 1/20 0.44
PRMT3 O60678 1/20 0.44
EP300 Q09472 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
SUMO2 P61956 1/20 0.40
SUMO1 P63165 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP2 Q9HC62 1/20 0.40
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808077 1.00 FUT8 (0.73) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL3697366 1.00 FUT8 (0.73) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL10782745 0.94 FUT8 (0.70) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL10782738 0.94 FUT8 (0.70) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL13881024 0.90 FUT8 (0.71) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL8114946 0.90 FUT8 (0.90) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL8072638 0.90 FUT8 (0.90) FUT8ENPP2PRMT1CYP1A2CYP2C9
SCHEMBL6808069 0.87 FUT8 (0.56) FUT8ENPP2PRMT1CYP2C9MAPK1
SCHEMBL29385758 0.87 FUT8 (0.56) FUT8ENPP2PRMT1CYP2C9MAPK1
SCHEMBL7197090 0.86 FUT8 (0.72) FUT8ENPP2PRMT1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373868-B1 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS SIGMA ALDRICH CO LLC (US) 2015-05-20 EP claimed
EP-1373868-A4 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS SIGMA ALDRICH CO (US) 2006-11-29 EP claimed
US-6887377-B2 Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications SIGMA-ALDRICH CO. (US) 2005-05-03 US claimed
EP-1373868-A1 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS Sigma-Aldrich Co. (US) 2004-01-02 EP claimed
US-20020108908-A1 Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications SIGMA-ALDRICH CO. 2002-08-15 US claimed
WO-2002061406-A1 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS SIGMA-ALDRICH CO. (US) 2002-08-08 WO claimed
EP-1373868-B1 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS SIGMA ALDRICH CO LLC (US) 2015-05-20 EP disclosed
US-8367823-B2 Colorants based N-halamines compositions and method of making and using BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-02-05 US disclosed
EP-2201069-A2 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING Board of Regents, The University of Texas System (US) 2010-06-30 EP disclosed
WO-2009039180-A2 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-26 WO disclosed
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-19 US disclosed
US-7438806-B2 Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications SIGMA-ALDRICH CO. (US) 2008-10-21 US disclosed
US-20070048800-A1 Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications SIGMA-ALDRICH CO. (US) 2007-03-01 US disclosed
US-20020108908-A1 Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications SIGMA-ALDRICH CO. 2002-08-15 US disclosed
WO-2002061406-A1 IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS SIGMA-ALDRICH CO. (US) 2002-08-08 WO disclosed
US-6022384-A Negative dyes and coloration process using them ZENECA LIMITED (GB) 2000-02-08 US disclosed
US-5968208-A Negative dyes and coloration process using them ZENECA LIMITED (GB) 1999-10-19 US disclosed
EP-0876430-A1 NEGATIVE DYES AND COLORATION PROCESS USING THEM ZENECA LIMITED (GB) 1998-11-11 EP disclosed
WO-1997019137-A1 NEGATIVE DYES AND COLORATION PROCESS USING THEM ZENECA LIMITED (GB) 1997-05-29 WO disclosed
US-4145340-A WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074825-A1 COLORANTS BASED N-HALAMINES COMPOSITIONS AND METHOD OF MAKING AND USING TYR, MPO, NISCH FUT8 651/4885ENPP2 3851/4885PRMT1 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.