⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157324 | 0.67 | MGLL (0.50) | — | |
| SCHEMBL95324 | 0.65 | MGLL (1.00) | — | |
| SCHEMBL8641616 | 0.65 | MGLL (0.70) | — | |
| SCHEMBL28676621 | 0.64 | — | — | |
| SCHEMBL5178729 | 0.62 | MGLL (0.48) | — | |
| SCHEMBL28373592 | 0.62 | — | — | |
| SCHEMBL2922210 | 0.62 | — | — | |
| SCHEMBL16104380 | 0.61 | — | — | |
| SCHEMBL138234 | 0.61 | — | — | |
| SCHEMBL6045734 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408157-B1 | Acid-cleavable compound | DANA FARBER CANCER INST INC (US) | 1996-03-06 | — | — | EP | claimed |
| EP-0408157-A1 | Acid-cleavable compound | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1991-01-16 | — | — | EP | claimed |
| EP-0191772-A4 | ACID-CLEAVABLE COMPOUND. | DANA FARBER CANCER INST INC (US) | 1988-11-09 | — | — | EP | claimed |
| EP-0191772-A1 | ACID-CLEAVABLE COMPOUND. | DANA FARBER CANCER INST INC (US) | 1986-08-27 | — | — | EP | claimed |
| WO-1986001409-A1 | ACID-CLEAVABLE COMPOUND | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-03-13 | — | — | WO | claimed |
| US-4542225-A | CROSSLINKING AGENTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1985-09-17 | — | — | US | claimed |
| EP-2850094-B1 | SELF-STABILIZING LINKER CONJUGATES | SEAGEN INC (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-108465112-B | Self-stabilizing linker conjugates | 西雅图基因公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20210300867-A1 | SELF-STABILIZING LINKER CONJUGATES | SEAGEN INC. | 2021-09-30 | — | — | US | disclosed |
| US-20180154011-A1 | SELF-STABILIZING LINKER CONJUGATES | SEAGEN INC. | 2018-06-07 | — | — | US | disclosed |
| US-9504756-B2 | Self-stabilizing linker conjugates | SEATTLE GENETICS, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150320879-A1 | SELF-STABILIZING LINKER CONJUGATES | SEATTLE GENETICS INC. | 2015-11-12 | — | — | US | disclosed |
| EP-2850094-A2 | SELF-STABILIZING LINKER CONJUGATES | Seattle Genetics, Inc. (US) | 2015-03-25 | — | — | EP | disclosed |
| US-20130309256-A1 | SELF-STABILIZING LINKER CONJUGATES | SEAGEN INC. | 2013-11-21 | — | — | US | disclosed |
| WO-2013173337-A2 | SELF-STABILIZING LINKER CONJUGATES | SEATTLE GENETICS, INC. (US) | 2013-11-21 | — | — | WO | disclosed |
| US-7795362-B2 | Olefin oligomers containing pendant maleimide groups | DESIGNER MOLECULES, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20060142517-A1 | Olefin oligomers containing pendant maleimide groups | DESIGNER MOLECULES, INC. | 2006-06-29 | — | — | US | disclosed |