Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877244 | 1.00 | — | — | |
| SCHEMBL3693855 | 0.97 | — | — | |
| SCHEMBL501949 | 0.87 | — | — | |
| SCHEMBL14759610 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL11579416 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL3695352 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL10631303 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL6745588 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL14760261 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL14759596 | 0.87 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101560-A1 | BIS[(ALKYLAMINO)ALKYL]AMINES | ALBEMARLE CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |