Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423383 | 0.75 | BTK (0.36) | — | |
| SCHEMBL6525604 | 0.74 | BTK (0.35) | — | |
| SCHEMBL1204289 | 0.70 | CYP19A1 (0.37) | ALDH1A1 | |
| SCHEMBL6525601 | 0.67 | POLB (0.31) | ALDH1A1 | |
| SCHEMBL1205561 | 0.66 | KMT2A (0.41) | ALDH1A1 | |
| SCHEMBL8390402 | 0.63 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL19545087 | 0.62 | BTK (0.49) | — | |
| SCHEMBL161076 | 0.62 | BTK (0.49) | — | |
| SCHEMBL17970213 | 0.62 | KMT2A (0.35) | ALDH1A1 | |
| SCHEMBL19544871 | 0.61 | BTK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188267-A2 | SUBSTITUTED AMIDES, METHODS OF MAKING, USE THEREOF FOR THE TREATMENT OF DISEASES SUCH AS CANCER | CGI Pharmaceuticals, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009039397-A2 | SUBSTITUTED AMIDES, METHODS OF MAKING, USE THEREOF FOR THE TREATMENT OF DISEASES SUCH AS CANCER | CGI PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | WO | disclosed |