Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338203 | 0.95 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL12102448 | 0.95 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL2977707 | 0.90 | ALDH1A1 (0.47) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL3692449 | 0.86 | KMT2A (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL2970252 | 0.85 | ALDH1A1 (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL12102445 | 0.85 | KMT2A (0.42) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL2962259 | 0.85 | ALDH1A1 (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL3418927 | 0.85 | ALDH1A1 (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL13202980 | 0.84 | ALDH1A1 (0.43) | KMT2AMEN1HPGDNPSR1ALDH1A1 | |
| SCHEMBL366030 | 0.84 | KMT2A (0.41) | KMT2AMEN1HPGDNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044685-A1 | NITROPHENYL MUSTARD ALCOHOLS, THEIR CORRESPONDING PHOSPHATES AND THEIR USE AS TARGETED CYTOTOXIC AGENTS | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-04-22 | — | — | WO | disclosed |