Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 16/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.63 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694396 | 0.99 | OPRM1 (0.63) | OPRM1OPRD1OPRK1S1PR5ABCB1 | |
| SCHEMBL3694536 | 0.96 | OPRM1 (0.62) | OPRM1OPRD1OPRK1S1PR5ABCB1 | |
| SCHEMBL3698501 | 0.93 | OPRM1 (0.57) | OPRM1OPRD1OPRK1ABCB1 | |
| SCHEMBL3694122 | 0.92 | OPRM1 (0.63) | OPRM1OPRD1OPRK1S1PR5ABCB1 | |
| SCHEMBL3693672 | 0.86 | OPRM1 (0.70) | OPRM1OPRD1OPRK1S1PR5 | |
| SCHEMBL3697396 | 0.86 | OPRM1 (0.63) | OPRM1OPRD1OPRK1ABCB1 | |
| SCHEMBL3690809 | 0.84 | OPRM1 (0.69) | OPRM1OPRD1OPRK1S1PR5ABCB1 | |
| SCHEMBL3699158 | 0.84 | OPRM1 (0.52) | OPRM1OPRD1OPRK1ABCB1 | |
| SCHEMBL3692086 | 0.82 | OPRM1 (0.68) | OPRM1OPRD1OPRK1ABCB1 | |
| SCHEMBL3690628 | 0.81 | OPRM1 (0.58) | OPRM1OPRD1OPRK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2208727-A1 | Diaryl ethers as opioid receptor antagonist | Eli Lilly & Company (US) | 2010-07-21 | — | — | EP | disclosed |