Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TOP2A | P11388 | 3/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546381 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL15502434 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL22579210 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9146620 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5184138 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Iodide SCHEMBL9805908 | 0.72 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7118334 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3815099 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10595590 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL17897071 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391209-A1 | SPUTUM DISSOLVING SUCTIONING SOLUTION FOR ENDOTRACHEAL AND TRACHEOSTOMY TUBES | Teleflex Medical Incorporated (US) | 2011-12-07 | — | — | EP | claimed |
| WO-2010088191-A1 | SPUTUM DISSOLVING SUCTIONING SOLUTION FOR ENDOTRACHEAL AND TRACHEOSTOMY TUBES | TELEFLEX MEDICAL INCORPORATED (US) | 2010-08-05 | — | — | WO | claimed |
| EP-2391632-A1 | BACTERIOSTATIC CATHETER LOCK CONTAINING GLYCEROL | Teleflex Medical Incorporated (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-2391209-A1 | SPUTUM DISSOLVING SUCTIONING SOLUTION FOR ENDOTRACHEAL AND TRACHEOSTOMY TUBES | Teleflex Medical Incorporated (US) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010088192-A1 | BACTERIOSTATIC CATHETER LOCK CONTAINING GLYCEROL | TELELFLEX MEDICAL INCORPORATED (US) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010088191-A1 | SPUTUM DISSOLVING SUCTIONING SOLUTION FOR ENDOTRACHEAL AND TRACHEOSTOMY TUBES | TELEFLEX MEDICAL INCORPORATED (US) | 2010-08-05 | — | — | WO | disclosed |
| EP-1833838-A2 | CATIONIC LIPOSOMES COMPRISING A CHARGE NEUTRAL COMPOUND AND A CATIONIC PHOSPHOLIPID | Applera Corporation, Applied Biosystems Group (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006065960-A2 | CATIONIC LIPOSOMES COMPRISING A CHARGE NEUTRAL COMPOUND AND A CATIONIC PHOSPHOLIPID | APPLERA CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006033713-A2 | METHODS FOR CIPROFLOXACIN INHALATION | CHIRON CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |