Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695872 | 1.00 | ACHE (0.59) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL13148035 | 1.00 | ACHE (0.59) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL12193088 | 0.91 | ACHE (0.60) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL12737547 | 0.91 | ACHE (0.60) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL12737530 | 0.91 | ACHE (0.60) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL13148280 | 0.90 | ACHE (0.47) | ACHEEPHX2EPHX1SIRT2SIRT1 | |
| SCHEMBL19651520 | 0.88 | ACHE (0.60) | ACHEEPHX2SIRT2SIRT1 | |
| SCHEMBL12737546 | 0.88 | ACHE (0.60) | ACHEEPHX2SIRT2SIRT1 | |
| SCHEMBL12737529 | 0.88 | ACHE (0.60) | ACHEEPHX2SIRT2SIRT1 | |
| SCHEMBL18532377 | 0.87 | ACHE (0.44) | ACHESIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112615-A1 | LYSINE DERIVATIVES FUNCTIONALISED WITH LIPIDS | DSM IP ASSETS B.V. (NL) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112615-A1 | LYSINE DERIVATIVES FUNCTIONALISED WITH LIPIDS | DSM IP ASSETS B.V. (NL) | 2010-10-07 | — | — | WO | disclosed |