Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730064 | 0.95 | KMT2A (0.57) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL31150525 | 0.93 | KMT2A (0.59) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL27546335 | 0.93 | KMT2A (0.59) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL16546594 | 0.93 | KMT2A (0.59) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL5822065 | 0.91 | KMT2A (0.61) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL2242019 | 0.89 | BCL9 (0.60) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL15549194 | 0.85 | KMT2A (0.66) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL10407329 | 0.85 | KMT2A (0.65) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL7500294 | 0.84 | KMT2A (0.58) | KMT2AMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL633267 | 0.84 | HSD17B3 (0.55) | KMT2AMAPTHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668599-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | Inflazome Limited (IE) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034690-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |
| EP-2593427-A1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007883-A1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |
| US-7976959-B2 | Organic electroluminescent element including bibenzothiopene containing organic compound and display device including the same | FUJI XEROX CO., LTD. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090243469-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE INCLUDING THE SAME | FUJI XEROX CO., LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-1725541-A2 | REACTIVE MESOGENIC CHARGE TRANSPORT COMPOUNDS CONTAINING AT LEAST TWO THIOPHENE GROUPS | MERCK PATENT GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005080369-A2 | REACTIVE MESOGENIC CHARGE TRANSPORT COMPOUNDS CONTAINING AT LEAST TWO THIOPHENE GROUPS | MERCK PATENT GMBH (DE) | 2005-09-01 | — | — | WO | disclosed |
| CN-1028174-C | Process and intermediates for preparing compounds having disubstituted acetylene moiety and retinoic acid-like biological activity | ALLERGAN INC (US) | 1995-04-12 | — | — | CN | disclosed |
| CN-1050385-A | Preparation has bioactive method and the intermediate that has the compound of disubstituted acetylene moiety of retinoic acid-like | ALLERGAN INC (US) | 1991-04-03 | — | — | CN | disclosed |