SCHEMBL2242019

SCHEMBL2242019

CCCC(=O)Oc1ccc(I)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.60
CTNNB1 P35222 1/20 0.60
KMT2A Q03164 10/20 0.55
ALDH1A1 P00352 4/20 0.55
MAPT P10636 2/20 0.55
LMNA P02545 1/20 0.55
HTT P42858 1/20 0.55
HSD17B10 Q99714 1/20 0.55
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
ESR1 P03372 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HIF1A Q16665 2/20 0.46
RECQL P46063 1/20 0.46
RAB9A P51151 1/20 0.46
PDGFRB P09619 1/20 0.43
PDGFRA P16234 1/20 0.43
ELANE P08246 1/20 0.42
CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023644 0.90 BCL9 (0.70) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL370103 0.89 KMT2A (0.52) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL27730064 0.87 KMT2A (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL31150525 0.86 KMT2A (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL27546335 0.86 KMT2A (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL16546594 0.86 KMT2A (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL4246892 0.84 KMT2A (0.63) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL6836918 0.84 BCL9 (0.64) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL898796 0.82 BCL9 (0.62) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL2292825 0.82 BCL9 (0.62) BCL9CTNNB1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
CN-120081908-A Multifunctional probe based on protein dynamic combination and preparation and application thereof 莎穆(上海)生物科技有限公司 2025-06-03 CN claimed
CN-119490560-A Tetrafunctional boron medicine compound, preparation method, application and pharmaceutical composition 东莞市人民医院 2025-02-21 CN claimed
US-20240180856-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY INDI MOLECULAR, INC. 2024-06-06 US claimed
CN-117700479-A Targeted prostate specific membrane antigen inhibitor, radioactive marker, preparation method and application thereof 原子高科股份有限公司 2024-03-15 CN claimed
US-20240053349-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) INDI MOLECULAR, INC. 2024-02-15 US claimed
US-11766414-B2 Compositions, delivery systems, and methods useful in tumor therapy INDI MOLECULAR, INC. (US) 2023-09-26 US claimed
US-11733246-B2 Compositions, imaging, and therapeutic methods targeting folate receptor 1 (FOLR1) INDI MOLECULAR, INC. (US) 2023-08-22 US claimed
US-20220229066-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) INDI MOLECULAR, INC. 2022-07-21 US claimed
US-20220211648-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY INDI MOLECULAR, INC. 2022-07-07 US claimed
US-10004760-B2 Microbubble complexes and methods of use GENERAL ELECTRIC COMPANY (US) 2018-06-26 US claimed
CN-107737335-A Microvesicle compound and application method 通用电气公司 2018-02-27 CN claimed
EP-2758081-B1 MICROBUBBLE COMPLEXES AND METHODS OF USE GEN ELECTRIC (US) 2017-02-08 EP claimed
US-20170007636-A1 MICROBUBBLE COMPLEXES AND METHODS OF USE GENERAL ELECTRIC COMPANY 2017-01-12 US claimed
EP-2758081-A1 MICROBUBBLE COMPLEXES AND METHODS OF USE General Electric Company (US) 2014-07-30 EP claimed
CN-103957940-A Microbubble complexes and methods of use GEN ELECTRIC 2014-07-30 CN claimed
WO-2013041500-A1 MICROBUBBLE COMPLEXES AND METHODS OF USE GENERAL ELECTRIC COMPANY (US) 2013-03-28 WO claimed
US-20130072854-A1 MICROBUBBLE COMPLEXES AND METHODS OF USE GENERAL ELECTRIC COMPANY (US) 2013-03-21 US claimed
CN-101380317-B Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD 2010-12-08 CN claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS ACE2, SARS1, TMPRSS2 BCL9 2830/4885CTNNB1 3842/4885KMT2A 4334/4885
US-20220229066-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) FOLR1, FOLR2, FOLH1 BCL9 1727/4885CTNNB1 3149/4885KMT2A 4195/4885
US-20240053349-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) FOLR1, FOLR2, FOLH1 BCL9 1727/4885CTNNB1 3149/4885KMT2A 4195/4885
US-11766414-B2 Compositions, delivery systems, and methods useful in tumor therapy TP53, BAX, RNASE1 BCL9 233/4885CTNNB1 3597/4885KMT2A 4697/4885
US-20220211648-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY TP53, BAX, RNASE1 BCL9 233/4885CTNNB1 3597/4885KMT2A 4697/4885
US-20240180856-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY TP53, BAX, RNASE1 BCL9 233/4885CTNNB1 3597/4885KMT2A 4697/4885
US-11733246-B2 Compositions, imaging, and therapeutic methods targeting folate receptor 1 (FOLR1) FOLR1, FOLR2, FOLH1 BCL9 1727/4885CTNNB1 3149/4885KMT2A 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.