SCHEMBL370108

SCHEMBL370108

C=CCOC(=O)C(=C)NC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
TSHR P16473 3/20 0.37
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
CRBN Q96SW2 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9362224 0.89 MAPT (0.34) MAPTCACNA1BAPBA1TSHR
SCHEMBL18448669 0.82 MAPT (0.55) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL11282327 0.80 MAPT (0.39) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL335110 0.78 MAPT (0.52) MAPTTSHRALDH1A1HSD17B10
SCHEMBL6269152 0.77
SCHEMBL22017 0.77
SCHEMBL1057516 0.77 TSHR (0.50) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL4823985 0.77
SCHEMBL8921614 0.77
SCHEMBL6884635 0.76 TSHR (0.50) MAPTTSHRCYP3A4TDP1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120013834-A1 LIQUID CRYSTAL FILM LG CHEM, LTD. (KR) 2012-01-19 US claimed
EP-2927741-B1 OPTICAL FILM LG CHEMICAL LTD (KR) 2022-01-05 EP disclosed
US-9891360-B2 Optical film LG CHEM, LTD. (KR) 2018-02-13 US disclosed
US-9703145-B2 Liquid crystal composition LG CHEM, LTD. (KR) 2017-07-11 US disclosed
US-9588369-B2 Liquid crystal cell LG CHEM, LTD. (KR) 2017-03-07 US disclosed
US-9182624-B2 Liquid crystal cell LG CHEM, LTD. (KR) 2015-11-10 US disclosed
US-20150301386-A1 LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2015-10-22 US disclosed
US-20150285978-A1 OPTICAL FILM SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2015-10-08 US disclosed
EP-2927301-A1 LIQUID CRYSTAL COMPOSITION LG Chem, Ltd. (KR) 2015-10-07 EP disclosed
EP-2927741-A1 OPTICAL FILM LG Chem, Ltd. (KR) 2015-10-07 EP disclosed
US-9151869-B2 Liquid crystal film LG CHEM, LTD. (KR) 2015-10-06 US disclosed
CN-104822801-A Liquid crystal composition LG CHEMICAL LTD 2015-08-05 CN disclosed
US-20140285752-A1 LIQUID CRYSTAL CELL LG CHEM, LTD. (KR) 2014-09-25 US disclosed
US-20140285751-A1 LIQUID CRYSTAL CELL LG CHEM, LTD. (KR) 2014-09-25 US disclosed
US-20120212692-A1 LIQUID CRYSTAL FILM LG CHEM, LTD. (KR) 2012-08-23 US disclosed
US-20120013834-A1 LIQUID CRYSTAL FILM LG CHEM, LTD. (KR) 2012-01-19 US disclosed