Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887589 | 0.98 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6888892 | 0.98 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6660361 | 0.90 | TSHR (0.55) | TSHRTHRBTDP1ALDH1A1EPHX1 | |
| SCHEMBL6657275 | 0.86 | TSHR (0.44) | TSHRTHRBPOLBHTTTDP1 | |
| SCHEMBL335110 | 0.81 | MAPT (0.52) | TSHRTHRBHTTALDH1A1MAPT | |
| SCHEMBL9556544 | 0.76 | TSHR (0.62) | TSHRPOLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL370108 | 0.76 | MAPT (0.41) | TSHRTDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL27617314 | 0.76 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25426 | 0.75 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5144090 | 0.75 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040234954-A1 | Surfaces that selectively bind to moieties | NATIONAL SCIENCE FOUNDATION | 2004-11-25 | — | — | US | disclosed |
| US-6486344-B1 | Polymer coatings with improved adhesion properties on metallic surfaces | MASSACHUSETTS, UNIVERSITY OF | 2002-11-26 | — | — | US | disclosed |