Urethane

Urethane

SCHEMBL3701773

CCOC(N)=O.CCOC(N)=S

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.75
ALDH1A1 P00352 6/20 0.43
LMNA P02545 3/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
CYP2D6 P10635 1/20 0.39
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
HTR1A P08908 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL3126043 0.90 ALOX15 (0.57) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL29070107 0.90 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Carbamic Acid SCHEMBL28045121 0.87 ALOX15 (0.55) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL7153966 0.87 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Carbamic Acid SCHEMBL29047215 0.87 ALOX15 (0.55) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL5792135 0.87 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8830978 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8505249 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL367439 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8136 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496465-A Liquid crystal poly (carbamate-thiourethane) elastomer and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-07-28 CN claimed
EP-1013410-B1 PROCESS FOR PREPARING OPTICAL THERMOPLASTIC URETHANE RESIN LENSES ASAHI LITE OPTICAL CO LTD (JP) 2005-11-16 EP claimed
CN-1175964-A Optical thermoplastic copolymer and method for producing same WASHI KOSAN KK (JP) 1998-03-11 CN claimed
US-5679756-A REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES OPTIMA INC. (US) 1997-10-21 US claimed
WO-2024020332-A1 OXIDATIVELY DEGRADING AND ROS SCAVENGING POLYMERS FOR MEDICAL APPLICATIONS BRIDGEWAY INNOVATIONS, LLC (US) 2024-01-25 WO disclosed
CN-116496465-A Liquid crystal poly (carbamate-thiourethane) elastomer and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-07-28 CN disclosed
CN-116034126-A Holographic recording material and preparation method thereof 科罗拉多大学评议会公司 2023-04-28 CN disclosed
CN-107383328-B Flexible bendable polyurethane optical material with barrier protection function, preparation method thereof, transparent flexible optical component and application thereof 烟台观复光电材料有限公司 2021-01-05 CN disclosed
US-8270089-B2 Thermoplastic polyurethane lenses with a specified weight percentage of urethane repeating units ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2012-09-18 US disclosed
EP-2155479-B1 THERMOPLASTIC POLYURETHANE LENSES WITH A SPECIFIED WEIGHT PERCENTAGE OF URETHANE REPEATING UNITS ESSILOR INT (FR) 2012-05-16 EP disclosed
US-20080246187-A1 Thermoplastic polyurethane lenses with a specified weight percentage of urethane repeating units ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2008-10-09 US disclosed
EP-1177090-B1 CONTINUOUS EXTRUSION-COMPRESSION MOLDING PROCESS FOR MAKING OPTICAL ARTICLES OPTIMA INC (US) 2007-12-26 EP disclosed
CN-1175964-A Optical thermoplastic copolymer and method for producing same WASHI KOSAN KK (JP) 1998-03-11 CN disclosed
CN-1175964-A Optical thermoplastic copolymer and method for producing same WASHI KOSAN KK (JP) 1998-03-11 CN disclosed
US-5679756-A REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES OPTIMA INC. (US) 1997-10-21 US disclosed
US-5679756-A REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES OPTIMA INC. (US) 1997-10-21 US disclosed
US-5679756-A REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES OPTIMA INC. (US) 1997-10-21 US disclosed
EP-0780413-A1 Optical thermoplastic thiourethane-urethane copolymers Optima Inc. (US) 1997-06-25 EP disclosed
EP-0780413-A1 Optical thermoplastic thiourethane-urethane copolymers Optima Inc. (US) 1997-06-25 EP disclosed
EP-0780413-A1 Optical thermoplastic thiourethane-urethane copolymers Optima Inc. (US) 1997-06-25 EP disclosed