SCHEMBL3701799

SCHEMBL3701799

CCCC(Oc1ccc(N)cc1)[Si](C)(C)O[Si](C)(C)C(CCC)Oc1ccc(N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.40
TSHR P16473 3/20 0.40
MAPK1 P28482 2/20 0.35
ALDH1A1 P00352 6/20 0.34
CYP3A4 P08684 3/20 0.34
MAPT P10636 5/20 0.33
RAB9A P51151 5/20 0.33
NPC1 O15118 5/20 0.33
PKM P14618 2/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TEAD4 Q15561 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3699085 0.92 TDP1 (0.37) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL10596567 0.84 TDP1 (0.38) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL11296970 0.83 PPARA (0.39) POLB
SCHEMBL10946658 0.83 SLC6A4 (0.37) TDP1MAPK1ALDH1A1MAPTKDM4E
SCHEMBL3713630 0.82 TSHR (0.34) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL10943323 0.78 MAPT (0.43) ALDH1A1MAPTRAB9ASMN1; SMN2HPGD
SCHEMBL10941780 0.78 KMT2A (0.50) TSHRMAPK1TP53KMT2A
SCHEMBL3697204 0.77 BCL9 (0.44) TSHRMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL10941521 0.76 MAPT (0.46) TDP1TSHRALDH1A1MAPTRAB9A
SCHEMBL9158314 0.75 TDP1 (0.39) TDP1TSHRMAPK1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415451-B2 Liquid crystal polyimide, liquid crystal resin composition containing same, and resin film for semiconductor elements MITSUBISHI CHEMICAL CORPORATION (JP) 2013-04-09 US disclosed
US-20120123050-A1 LIQUID CRYSTAL POLYIMIDE, LIQUID CRYSTAL RESIN COMPOSITION CONTAINING SAME, AND RESIN FILM FOR SEMICONDUCTOR ELEMENTS MITSUBISHI CHEMICAL CORPORATION (JP) 2012-05-17 US disclosed
US-4499149-A ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES M&T CHEMICALS INC. (US) 1985-02-12 US disclosed
US-4480009-A POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE M&T CHEMICALS INC. (US) 1984-10-30 US disclosed
EP-0015720-B1 COPOLYMERIC COATING COMPOSITIONS M & T CHEMICALS, INC. (US) 1983-10-12 EP disclosed
US-4395527-A POLYIMIDES FROM AMINOPOLYSILOXANES M & T CHEMICALS INC. (US) 1983-07-26 US disclosed
EP-0054426-A2 Improvements in or relating to siloxanes M & T CHEMICALS, INC. (US) 1982-06-23 EP disclosed
EP-0015720-A1 Copolymeric coating compositions M & T CHEMICALS, INC. (US) 1980-09-17 EP disclosed