SCHEMBL3713630

SCHEMBL3713630

CCCCCC(Oc1ccc(N)cc1)[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C(CCCCC)Oc1ccc(N)cc1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
SLC2A1 P11166 1/20 0.34
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PDE4D Q08499 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GRM2 Q14416 1/20 0.30
PLA2G2A P14555 1/20 0.30
TLR8 Q9NR97 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3699085 0.90 TDP1 (0.37) TSHRTDP1CYP3A4NPC1RAB9A
SCHEMBL9158314 0.84 TDP1 (0.39) TSHRTDP1SLC2A1LMNACYP1A2
SCHEMBL3701799 0.82 TDP1 (0.40) TSHRTDP1LMNACYP1A2CYP3A4
SCHEMBL3700151 0.81 MGLL (0.42) TSHRCYP3A4NPC1RAB9AMAPT
SCHEMBL9448649 0.76 NR5A1 (0.44) TSHRLMNACYP1A2CYP3A4CYP2C19
SCHEMBL17225179 0.74 TSHR (0.43) TSHRKDM4EALDH1A1PLA2G2A
SCHEMBL10595641 0.74 TDP1 (0.44) TSHRTDP1SLC2A1LMNACYP1A2
SCHEMBL20226687 0.74 TDP1 (0.44) TSHRTDP1SLC2A1LMNACYP1A2
SCHEMBL25283342 0.72 SLC2A1 (0.44) TSHRTDP1SLC2A1LMNACYP1A2
SCHEMBL7908097 0.72 SLC2A1 (0.44) TSHRTDP1SLC2A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415451-B2 Liquid crystal polyimide, liquid crystal resin composition containing same, and resin film for semiconductor elements MITSUBISHI CHEMICAL CORPORATION (JP) 2013-04-09 US disclosed
US-20120123050-A1 LIQUID CRYSTAL POLYIMIDE, LIQUID CRYSTAL RESIN COMPOSITION CONTAINING SAME, AND RESIN FILM FOR SEMICONDUCTOR ELEMENTS MITSUBISHI CHEMICAL CORPORATION (JP) 2012-05-17 US disclosed