Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236165 | 0.86 | TSHR (0.34) | ABCC4MAPTHDAC1HDAC2FFAR3 | |
| SCHEMBL10546961 | 0.83 | GRIK1 (0.39) | ABCC4MAPTGRIK1GRIK2HDAC1 | |
| SCHEMBL11736110 | 0.82 | GRIK1 (0.36) | ABCC4MAPTGRIK1GRIK2HDAC1 | |
| SCHEMBL5069039 | 0.77 | TSHR (0.36) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| SCHEMBL31636 | 0.77 | GRIK1 (0.48) | ABCC4MAPTGRIK1GRIK2CYP2C19 | |
| SCHEMBL7756489 | 0.75 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1TSHR | |
| SCHEMBL27930477 | 0.75 | GRIK1 (0.41) | GRIK1GRIK2HDAC1HDAC2FFAR3 | |
| SCHEMBL5060532 | 0.75 | GRIK1 (0.37) | GRIK1GRIK2CPA1TSHRFAAH | |
| SCHEMBL1484027 | 0.75 | HDAC1 (0.46) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Potassium SCHEMBL31299609 | 0.74 | GRIK1 (0.46) | ABCC4MAPTGRIK1GRIK2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642073-B2 | Using mixture comprising modified alcohol dehydrogenase, ammonia, nicotinamide and 2-ketoacid to generate preferential amino acids | CODEXIS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20080076162-A1 | Using mixture comprising modified alcohol dehydrogenase, ammonia, nicotinamide and 2-ketoacid to generate preferential amino acids | BIOCATALYTICS, INC. | 2008-03-27 | — | — | US | disclosed |
| US-7202070-B2 | Generating phenylalanine and leucine using mutant enzymatic polypeptide; generate mutant enzyme, aminate ketoacid, recover amino acids | BIOCATALYTICS, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20020061564-A1 | Generating phenylalanine and leucine using mutant enzymatic polypeptide; generate mutant enzyme, aminate ketoacid, recover amino acids | CODEXIS, INC. | 2002-05-23 | — | — | US | disclosed |
| WO-2002036742-A2 | METHOD FOR CHEMICAL TRANSFORMATION USING A MUTATED ENZYME | BIOCATALYTICS, INC. (US) | 2002-05-10 | — | — | WO | disclosed |
| US-4245122-A | USING TRICAPRYLMETHYLAMMONIUM CHLORIDE AS A PHASE TRANSFER AGENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-01-13 | — | — | US | disclosed |