Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124810 | 0.88 | CES2 (0.44) | TSHRFAAHCES2CES1LMNA | |
| SCHEMBL3908897 | 0.86 | CES2 (0.52) | TSHRFAAHCES2CES1LMNA | |
| SCHEMBL12857912 | 0.82 | — | — | |
| SCHEMBL12857629 | 0.82 | — | — | |
| SCHEMBL5088544 | 0.82 | — | — | |
| SCHEMBL3701829 | 0.77 | ABCC4 (0.38) | TSHRFAAHCES2CES1FFAR3 | |
| SCHEMBL27930477 | 0.77 | GRIK1 (0.41) | TSHRFAAHCES2CES1FFAR3 | |
| SCHEMBL5060532 | 0.77 | GRIK1 (0.37) | TSHRFAAHCES2CES1MAPK1 | |
| SCHEMBL17112013 | 0.77 | GRIK1 (0.35) | TSHRCES2CES1FFAR3HDAC3 | |
| SCHEMBL14641477 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039361-A2 | Use of immunomodulatory compounds | Eisai R&D Management Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |