Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700989 | 0.81 | LPAR1 (0.46) | LPAR1LPAR3MAPTKDM4ECYP2C9 | |
| SCHEMBL3702854 | 0.78 | LPAR1 (0.47) | LPAR1LPAR3MAPTKDM4ESCN5A | |
| SCHEMBL4029141 | 0.72 | LPAR1 (0.62) | LPAR1LPAR3MAPTKDM4ECYP2C9 | |
| SCHEMBL1247389 | 0.70 | SCN9A (0.45) | MAPTKDM4ESCN5ASCN9ATSHR | |
| SCHEMBL2336119 | 0.69 | LPAR1 (0.49) | LPAR1LPAR3MAPTKDM4ESCN5A | |
| SCHEMBL3711311 | 0.68 | LPAR1 (0.43) | LPAR1LPAR3MAPTKDM4ESCN5A | |
| SCHEMBL343051 | 0.66 | LPAR1 (0.56) | LPAR1LPAR3MAPTKDM4ECYP2C9 | |
| SCHEMBL30472637 | 0.65 | SMN1; SMN2 (0.49) | LPAR1LPAR3KDM4ECYP2C9CYP1A2 | |
| SCHEMBL3706444 | 0.65 | LPAR1 (0.46) | LPAR1LPAR3MAPTKDM4ECYP2C9 | |
| SCHEMBL4035675 | 0.63 | MAPT (0.67) | LPAR1LPAR3MAPTKDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |