Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046737 | 0.88 | HTR3A (0.36) | HRH4HTR3AALDH1A1GAAGFER | |
| SCHEMBL3046733 | 0.88 | HTR3A (0.36) | HRH4HTR3AALDH1A1GAAGFER | |
| SCHEMBL2672027 | 0.88 | HTR3A (0.36) | HRH4HTR3AALDH1A1GAAGFER | |
| SCHEMBL3042561 | 0.86 | KDM4E (0.47) | HRH4HTR3AALDH1A1GAACETP | |
| SCHEMBL3059598 | 0.86 | KDM4E (0.47) | HRH4HTR3AALDH1A1GAACETP | |
| SCHEMBL3052755 | 0.85 | CCR1 (0.38) | HRH4HTR3AMAPTCCR1 | |
| SCHEMBL3052760 | 0.85 | CCR1 (0.38) | HRH4HTR3AMAPTCCR1 | |
| SCHEMBL3880704 | 0.84 | HTR3A (0.35) | HRH4HTR3AALDH1A1GAAGFER | |
| SCHEMBL4072273 | 0.82 | CETP (0.37) | HRH4HTR3AALDH1A1GAAGFER | |
| SCHEMBL589593 | 0.81 | CETP (0.33) | HRH4HTR3AALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205608-A1 | PREPARATION OF DIHYDROTHIENO Ý3, 2-D¨PYRIMIDINES AND INTERMEDIATES USED THEREIN | Boehringer Ingelheim International GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009052138-A1 | PREPARATION OF DIHYDROTHIENO [3, 2-D] PYRIMIDINES AND INTERMEDIATES USED THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |