Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095023 | 1.00 | CA2 (0.40) | CA2CA4EPHX2TDP1MME | |
| SCHEMBL1396442 | 0.88 | EPHX2 (0.46) | CA2CA4EPHX2GNPATGPR84 | |
| SCHEMBL1396439 | 0.88 | EPHX2 (0.46) | CA2CA4EPHX2GNPATGPR84 | |
| SCHEMBL4992798 | 0.86 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 | |
| SCHEMBL39257 | 0.86 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 | |
| SCHEMBL414800 | 0.86 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 | |
| SCHEMBL5825896 | 0.86 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 | |
| SCHEMBL15637714 | 0.86 | CA2 (0.45) | CA2CA4TDP1MMESMN1; SMN2 | |
| SCHEMBL472923 | 0.86 | EPHX2 (0.48) | EPHX2SMN1; SMN2GPR84 | |
| SCHEMBL472928 | 0.86 | EPHX2 (0.48) | EPHX2SMN1; SMN2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016154591-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |
| US-20100112558-A1 | Probe Bead Synthesis and Use | Gao, Xiaolian (US) | 2010-05-06 | — | — | US | disclosed |