Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.59 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712097 | 0.86 | MAPT (0.52) | CDC7DBF4KDM4ETRPM8MAPT | |
| SCHEMBL3705885 | 0.84 | CDC7 (0.59) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL3707390 | 0.83 | CDC7 (0.58) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL7893016 | 0.81 | CDC7 (0.56) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL1983007 | 0.81 | CDC7 (0.56) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL28295520 | 0.81 | CDC7 (0.64) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL3711151 | 0.81 | CDC7 (0.59) | CDC7DBF4CCNCCDK8MAOA | |
| SCHEMBL28295522 | 0.80 | CDC7 (0.67) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL3707514 | 0.80 | CDC7 (0.55) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL3717089 | 0.80 | CDC7 (0.52) | CDC7DBF4KDM4EALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |