Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.59 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.59 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702956 | 0.81 | CDC7 (0.59) | CDC7DBF4CCNCCDK8MAOA | |
| SCHEMBL22259665 | 0.80 | GUSB (0.47) | GUSBEGFR | |
| SCHEMBL3709678 | 0.79 | CDC7 (0.56) | CDC7DBF4JAK2JAK3 | |
| SCHEMBL7883332 | 0.79 | CDC7 (0.56) | CDC7DBF4JAK2JAK3 | |
| SCHEMBL3708608 | 0.79 | CDC7 (0.53) | CDC7DBF4JAK3 | |
| SCHEMBL31072377 | 0.79 | MAOA (0.57) | CCNCCDK8MAOAKDRMMP13 | |
| SCHEMBL3712097 | 0.78 | MAPT (0.52) | CDC7DBF4CCNCCDK8MAOA | |
| SCHEMBL3714645 | 0.78 | EGFR (0.60) | CCNCCDK8MAOAGUSBMMP13 | |
| SCHEMBL23794795 | 0.78 | CDC7 (0.79) | CDC7DBF4 | |
| SCHEMBL1646106 | 0.77 | JMJD6 (0.55) | CCNCCDK8MAOAKDRMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |