Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705536 | 0.94 | LPAR1 (0.51) | LPAR1LPAR3LPAR2WNT3AHIF1A | |
| SCHEMBL3705461 | 0.93 | LPAR1 (0.40) | LPAR1LPAR3LPAR2WNT3AHIF1A | |
| SCHEMBL2335542 | 0.87 | LPAR1 (0.61) | LPAR1LPAR3LPAR2ROCK2ABCC3 | |
| SCHEMBL3710547 | 0.86 | LPAR1 (0.57) | LPAR1LPAR3LPAR2WNT3AROCK2 | |
| SCHEMBL3712501 | 0.86 | LPAR1 (0.59) | LPAR1LPAR3LPAR2HIF1AROCK2 | |
| SCHEMBL3712525 | 0.86 | LPAR1 (0.57) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL3704739 | 0.86 | LPAR1 (0.42) | LPAR1LPAR3LPAR2HIF1AABCC3 | |
| SCHEMBL3714425 | 0.85 | LPAR1 (0.48) | LPAR1LPAR3LPAR2HIF1AABCC3 | |
| SCHEMBL3709662 | 0.85 | LPAR1 (0.56) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL3708426 | 0.84 | LPAR1 (0.50) | LPAR1LPAR3LPAR2WNT3AABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |