Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3703083 | 0.93 | LPAR1 (0.47) | LPAR1LPAR3LPAR2HIF1AWNT3A | |
| SCHEMBL3704739 | 0.88 | LPAR1 (0.42) | LPAR1LPAR3LPAR2HIF1APTGER4 | |
| SCHEMBL3705536 | 0.86 | LPAR1 (0.51) | LPAR1LPAR3LPAR2HIF1AWNT3A | |
| SCHEMBL3708581 | 0.86 | LPAR1 (0.41) | LPAR1LPAR3LPAR2HIF1ALMNA | |
| SCHEMBL3705147 | 0.82 | LPAR1 (0.43) | LPAR1LPAR3LPAR2LMNASLC26A6 | |
| SCHEMBL3705433 | 0.82 | LPAR1 (0.55) | LPAR1LPAR3LPAR2WNT3ARET | |
| SCHEMBL2335478 | 0.82 | LPAR1 (0.51) | LPAR1LPAR3LPAR2LMNASLC26A6 | |
| SCHEMBL3703620 | 0.82 | LPAR1 (0.36) | LPAR1LPAR3LPAR2SLC26A6KDM4E | |
| SCHEMBL3702178 | 0.81 | LPAR1 (0.49) | LPAR1LPAR3LPAR2HIF1ASLC26A6 | |
| SCHEMBL3715780 | 0.80 | LPAR1 (0.47) | LPAR1LPAR3LPAR2SLC26A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |