Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.52 |
| ▸ | THRB | P10828 | 10/20 | 0.52 |
| ▸ | THRA | P10827 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233002 | 0.89 | RORC (0.55) | RORCTHRBTHRA | |
| SCHEMBL3707379 | 0.88 | RORC (0.57) | RORCTHRBTHRA | |
| SCHEMBL3707575 | 0.88 | RORC (0.46) | RORCTHRB | |
| SCHEMBL3221894 | 0.86 | RORC (0.58) | RORCTHRBTHRA | |
| SCHEMBL3217778 | 0.86 | RORC (0.52) | RORCTHRBTHRA | |
| SCHEMBL3701579 | 0.85 | RORC (0.49) | RORCTHRBTHRA | |
| SCHEMBL3706521 | 0.85 | RORC (0.53) | RORCTHRBTHRA | |
| SCHEMBL3709382 | 0.85 | RORC (0.51) | RORCTHRBTHRA | |
| SCHEMBL3706058 | 0.85 | RORC (0.51) | RORCTHRBTHRA | |
| SCHEMBL3715368 | 0.84 | RORC (0.61) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |