Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236287 | 0.93 | TSHR (0.36) | TSHRCES1CES2ALDH1A1HPGD | |
| SCHEMBL18190223 | 0.88 | CES1 (0.35) | TSHRCES1CES2ALDH1A1TP53 | |
| SCHEMBL6116158 | 0.84 | TSHR (0.52) | TSHRCES2ALDH1A1HPGDATM | |
| SCHEMBL1067977 | 0.82 | CES1 (0.37) | TSHRCES1CES2ALDH1A1TP53 | |
| SCHEMBL10940919 | 0.80 | TSHR (0.52) | TSHRCES2ALDH1A1HPGDATM | |
| SCHEMBL8063861 | 0.79 | CES1 (0.34) | TSHRCES1CES2ALDH1A1HPGD | |
| SCHEMBL3128838 | 0.78 | CES1 (0.39) | TSHRCES1CES2ALDH1A1HPGD | |
| SCHEMBL10870503 | 0.78 | CES1 (0.33) | TSHRCES1CES2ALDH1A1TP53 | |
| SCHEMBL3394141 | 0.77 | ALDH1A1 (0.32) | CES1CES2ALDH1A1 | |
| SCHEMBL1879950 | 0.76 | TSHR (0.47) | TSHRCES2ALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519026-B2 | Waterborne polymeric dispersions | NUPLEX RESINS B.V. (NL) | 2013-08-27 | — | — | US | disclosed |
| US-20130109816-A1 | PROCESSES FOR REMOVING SULFUR-CONTAINING END GROUPS FROM POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20100331453-A1 | Waterborne Polymeric Dispersions | NUPLEX RESINS B.V. (NL) | 2010-12-30 | — | — | US | disclosed |