Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131404 | 1.00 | IDH1 (0.35) | IDH1 | |
| SCHEMBL10585803 | 0.79 | IDH1 (0.35) | IDH1 | |
| SCHEMBL10585806 | 0.79 | IDH1 (0.35) | IDH1 | |
| SCHEMBL3513116 | 0.78 | IDH1 (0.40) | IDH1 | |
| SCHEMBL7536857 | 0.78 | IDH1 (0.40) | IDH1 | |
| SCHEMBL7916536 | 0.78 | IDH1 (0.40) | IDH1 | |
| SCHEMBL8321135 | 0.78 | IDH1 (0.40) | IDH1 | |
| SCHEMBL11436250 | 0.78 | IDH1 (0.40) | IDH1 | |
| SCHEMBL739613 | 0.78 | IDH1 (0.39) | IDH1 | |
| SCHEMBL5082139 | 0.77 | IDH1 (0.36) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20030199709-A1 | Process for the preparation of enantiomerically pure pyrethroid insecticides | SYNGENTA LIMITED (GB) | 2003-10-23 | — | — | US | disclosed |
| US-6093726-A | AN INSECTICIDES, ACARICIDES OR NEMATICIDES | ZENECA LIMITED (GB) | 2000-07-25 | — | — | US | disclosed |
| US-5849754-A | Bicyclic amine derivatives | ZENECA LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199709-A1 | Process for the preparation of enantiomerically pure pyrethroid insecticides | CYP4B1, CYP4A11, DDT | IDH1 318/4885 |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | NISCH, AADAC, ACHE | IDH1 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.