Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66965 | 0.81 | CYP1A2 (0.55) | SLC7A5CPB2SLC1A1 | |
| SCHEMBL15426321 | 0.81 | CYP1A2 (0.55) | SLC7A5CPB2SLC1A1 | |
| SCHEMBL11829249 | 0.79 | SLC1A1 (0.50) | SLC7A5MAOAMAOBCPN1CPB2 | |
| SCHEMBL1067198 | 0.79 | PLA2G10 (0.50) | SLC7A5MAOAMAOBCPN1CPB2 | |
| SCHEMBL3693497 | 0.77 | SLC1A1 (0.35) | SLC1A1 | |
| SCHEMBL288729 | 0.77 | SLC7A5 (0.67) | SLC7A5NOS3NOS1NOS2GRIA2 | |
| SCHEMBL288636 | 0.77 | SLC7A5 (0.67) | SLC7A5NOS3NOS1NOS2GRIA2 | |
| SCHEMBL755879 | 0.77 | KDM6B (0.54) | SLC7A5MAOAMAOBCPN1CPB2 | |
| SCHEMBL385392 | 0.77 | SLC7A5 (0.67) | SLC7A5NOS3NOS1NOS2GRIA2 | |
| SCHEMBL29475725 | 0.77 | SLC7A5 (0.67) | SLC7A5NOS3NOS1NOS2GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |