Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 10/20 | 0.34 |
| ▸ | CTSD | P07339 | 9/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694575 | 0.82 | AKR1B1 (0.34) | SLC1A1BACE1CTSDPPARGPPARA | |
| SCHEMBL3704633 | 0.77 | SLC7A5 (0.44) | SLC1A1 | |
| SCHEMBL1068884 | 0.75 | SLC7A5 (0.36) | SLC1A1PPARGPPARALDHA | |
| SCHEMBL3697063 | 0.73 | PPARA (0.43) | PPARGPPARA | |
| SCHEMBL28393885 | 0.72 | NOS2 (0.37) | BACE1CTSDADRB1 | |
| SCHEMBL3694002 | 0.72 | DPP4 (0.37) | PPARGPPARA | |
| SCHEMBL28726849 | 0.71 | IDO1 (0.34) | BACE1ADRB1 | |
| SCHEMBL66965 | 0.70 | CYP1A2 (0.55) | SLC1A1 | |
| SCHEMBL15426321 | 0.70 | CYP1A2 (0.55) | SLC1A1 | |
| SCHEMBL1905728 | 0.69 | KDM4E (0.43) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |