SCHEMBL3705370

SCHEMBL3705370

Oc1ccc2ccccc2c1/N=N/c1ccc(/N=N/c2ccc(/N=N/c3c(O)ccc4ccccc34)cc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.90
L3MBTL1 Q9Y468 7/20 0.90
KMT2A Q03164 7/20 0.90
MEN1 O00255 6/20 0.90
TDP1 Q9NUW8 5/20 0.90
HSP90AA1 P07900 3/20 0.90
LMNA P02545 2/20 0.90
GAA P10253 2/20 0.90
ALPL P05186 1/20 0.90
ALPI P09923 1/20 0.90
ALPG P10696 1/20 0.90
CASP3 P42574 1/20 0.90
RECQL P46063 1/20 0.90
MMP14 P50281 1/20 0.90
SENP8 Q96LD8 1/20 0.90
SENP7 Q9BQF6 1/20 0.90
SENP6 Q9GZR1 1/20 0.90
THRB P10828 4/20 0.89
MAPK1 P28482 4/20 0.84
ALDH1A1 P00352 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3705371 1.00 MAPT (0.90) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL3705373 1.00 MAPT (0.90) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL10294618 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL506289 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL29353869 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL52298 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL20138219 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL1942693 0.96 THRB (0.96) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL7614146 0.95 MAPT (0.81) MAPTL3MBTL1KMT2AMEN1TDP1
SCHEMBL7614142 0.95 MAPT (0.81) MAPTL3MBTL1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 US disclosed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 WO disclosed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 US disclosed
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed
US-4179395-A LIQUID CRYSTALS FOR USE IN DISPLAYS GENERAL ELECTRIC COMPANY (US) 1979-12-18 US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed