Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062332 | 0.82 | KCNQ3 (0.48) | CHRNA7RAB9APKMMAPT | |
| SCHEMBL3063119 | 0.82 | GAA (0.58) | RAB9APKMMAPT | |
| SCHEMBL3066509 | 0.82 | GAA (0.51) | RAB9APKMMAPT | |
| SCHEMBL3057626 | 0.82 | KDM4E (0.43) | CHRNA7PKMGFERPPARGP2RX3 | |
| SCHEMBL3059637 | 0.81 | GAA (0.51) | RAB9APKMMAPT | |
| SCHEMBL3061602 | 0.81 | RAB9A (0.50) | CHRNA7RAB9APKMMAPT | |
| SCHEMBL3054652 | 0.81 | GAA (0.50) | RAB9APKMMAPT | |
| SCHEMBL3062716 | 0.77 | SCN9A (0.51) | RAB9A | |
| SCHEMBL3062655 | 0.76 | PPARG (0.45) | CHRNA7RAB9AGFERHTR2CPPARG | |
| SCHEMBL3061624 | 0.76 | STAT3 (0.48) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |