Taurocholic Acid

Taurocholic Acid

SCHEMBL3706

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 7/20 1.00
SLC10A2 Q12908 4/20 1.00
SLC10A1 Q14973 3/20 1.00
TSHR P16473 1/20 0.85
RAB9A P51151 1/20 0.85
LMNA P02545 1/20 0.85
BLM P54132 1/20 0.85
NR1H4 Q96RI1 3/20 0.81
ABCC4 O15439 2/20 0.81
ABCB11 O95342 2/20 0.81
PLA2G1B P04054 1/20 0.81
ENPP2 Q13822 1/20 0.81
KMT2A Q03164 2/20 0.75
CA1 P00915 2/20 0.71
CA2 P00918 2/20 0.71
CYP3A4 P08684 3/20 0.71
PDE3A Q14432 1/20 0.71
MEN1 O00255 1/20 0.70
SLCO1B3 Q9NPD5 1/20 0.70
SLCO1B1 Q9Y6L6 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurocholic Acid SCHEMBL13851619 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL3705 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL5083946 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL24001492 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL435030 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL24486612 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL10696857 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL22852508 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL20493965 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A
Taurocholic Acid SCHEMBL15292871 1.00 GPBAR1 (1.00) GPBAR1SLC10A2SLC10A1TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
CN-122075500-A Application of pig cholic acid bile acid component in preparation of medicine for treating irritable bowel syndrome 2026-05-26 CN claimed
US-20260139227-A1 ADIPOSE-DERIVED REGENERATIVE CELL PREPARATIONS BLUE CELL THERAPEUTICS APS (DK) 2026-05-21 US claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
WO-2026104892-A2 DEVICES, COMPOSITIONS, AND METHODS FOR IN VIVO FLUORESCENCE IMAGING GLYCANSCAN INTERNATIONAL BV (NL) 2026-05-21 WO claimed
CN-114195852-B Preparation method of 3 beta, 7 beta-dihydroxyl-5 beta-cholanic acid 中山百灵生物技术股份有限公司 2026-05-19 CN claimed
CN-119791058-B Pain rheumatism heat syndrome subtype modeling method, biomarker group application and detection method 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2026-05-19 CN claimed
CN-122056828-A Industrial preparation method of vitamin K1 micelle injection preparation 浙江创新生物有限公司 2026-05-19 CN claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN claimed
EP-0058000-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1986-01-02 EP claimed
US-4554249-A Method for the quantitative determination of physiological components in biological fluids AMANO PHARMACEUTICAL COMPANY LIMITED (JP) 1985-11-19 US claimed
EP-0127535-A2 Pharmaceutical compositions containing insulin HADASSAH MEDICAL ORGANIZATION (IL) 1984-12-05 EP claimed
US-4486532-A IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM TNANBE SEIYAKU CO., LTD. (JP) 1984-12-04 US claimed
EP-0058000-A2 Cosmetic composition UNILEVER PLC (GB) 1982-08-18 EP claimed
US-4164573-A INSULIN GALINSKY ALVIN M 1979-08-14 US claimed
US-4158707-A Parenteral preparations HOFFMANN-LA ROCHE INC. (US) 1979-06-19 US claimed
US-4115313-A FATTY ACIDS, PHOSPHOLIPIDS, STEROIDS LYON IRVING 1978-09-19 US claimed
US-4072575-A PARA-COUMARIC ACID, ACETAZOLAMIDE MCDONNELL DOUGLAS CORPORATION (US) 1978-02-07 US claimed
US-3937815-A BILE ACID SPA--Societa Prodotti Antibiotici S.p.A. (IT) 1976-02-10 US claimed