Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 1.00 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 1.00 |
| ▸ | SLC10A1 | Q14973 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | RAB9A | P51151 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | BLM | P54132 | 1/20 | 0.85 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.81 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.81 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.81 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.70 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurocholic Acid SCHEMBL435030 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL13851619 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL5083946 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL15292871 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL24001492 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL3705 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL10696857 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL22852508 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL20493965 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A | |
| Taurocholic Acid SCHEMBL3706 | 1.00 | GPBAR1 (1.00) | GPBAR1SLC10A2SLC10A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256099-A1 | Safe Use of Bile Acids and Their Salts as Enhancers for Nasal Delivery of Pharmaceuticals | AMPHASTAR PHARMACEUTICALS INC (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230181500-A1 | Naloxone Pharmaceutical Formulations for Intranasal (IN) Delivery | AMPHASTAR PHARMACEUTICALS INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11351268-B2 | FGF21 C-terminal peptide optimization | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181500-A1 | Naloxone Pharmaceutical Formulations for Intranasal (IN) Delivery | SLC10A1, SLC10A2, OPRK1 | GPBAR1 14/4885SLC10A2 2/4885SLC10A1 1/4885 |
| US-11351268-B2 | FGF21 C-terminal peptide optimization | FGF23, FGFR1, FGFR3 | GPBAR1 543/4885SLC10A2 478/4885SLC10A1 295/4885 |
| US-20230256099-A1 | Safe Use of Bile Acids and Their Salts as Enhancers for Nasal Delivery of Pharmaceuticals | SLC10A2, ABCB11, SLC10A1 | GPBAR1 8/4885SLC10A2 1/4885SLC10A1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.