Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000247 | 0.83 | TDP1 (0.53) | PLAUTDP1LMNAL3MBTL1MAPT | |
| SCHEMBL12146096 | 0.79 | MTNR1A (0.36) | PLAUTDP1LMNAL3MBTL1MAPT | |
| SCHEMBL23375370 | 0.78 | KDM4E (0.55) | PLAUTDP1LMNAMAPTTSHR | |
| SCHEMBL20808087 | 0.76 | PLAU (0.45) | PLAUTDP1PKMLMNAL3MBTL1 | |
| SCHEMBL18600902 | 0.76 | APP (0.54) | PLAULMNATSHRSMN1; SMN2 | |
| SCHEMBL2005246 | 0.75 | PLAU (0.40) | PLAUTDP1LMNAL3MBTL1MAPT | |
| SCHEMBL23705809 | 0.74 | PLAU (0.43) | PLAUTDP1PKMLMNAL3MBTL1 | |
| SCHEMBL30042575 | 0.74 | PLAU (0.43) | PLAUTDP1PKMLMNAL3MBTL1 | |
| SCHEMBL25298000 | 0.74 | ACACB (0.39) | TDP1LMNAKMT2APSMB5ALDH1A1 | |
| SCHEMBL25298001 | 0.74 | ACACB (0.39) | TDP1LMNAKMT2APSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396295-A1 | PHENOXY ACETIC ACID DERIVATIVES | Merck Serono S.A. (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |