Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710136 | 0.94 | LPAR1 (0.42) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3707275 | 0.92 | LPAR1 (0.40) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3706752 | 0.86 | LPAR1 (0.45) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3703582 | 0.85 | LPAR1 (0.55) | LPAR1LPAR3LPAR2RORCMAPT | |
| SCHEMBL3700498 | 0.84 | SCN9A (0.40) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL1246383 | 0.80 | SCN9A (0.51) | SCN9ASCN5ARORCMAPTKDM4E | |
| SCHEMBL3712822 | 0.80 | LPAR1 (0.43) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3713322 | 0.79 | LPAR1 (0.47) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3707845 | 0.79 | LPAR1 (0.46) | SCN9ASCN5ALPAR1LPAR3LPAR2 | |
| SCHEMBL3704851 | 0.79 | LPAR1 (0.42) | SCN9ASCN5ALPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |