Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336975 | 0.91 | LPAR1 (0.60) | LPAR1LPAR3LPAR2NLRP3SCN9A | |
| SCHEMBL3705664 | 0.91 | LPAR1 (0.47) | LPAR1LPAR3LPAR2NLRP3SCN9A | |
| SCHEMBL2335478 | 0.90 | LPAR1 (0.51) | LPAR1LPAR3LPAR2NLRP3ABCC3 | |
| SCHEMBL2336267 | 0.89 | LPAR1 (0.54) | LPAR1LPAR3LPAR2NLRP3SCN9A | |
| SCHEMBL2335063 | 0.87 | LPAR1 (0.57) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL3715780 | 0.87 | LPAR1 (0.47) | LPAR1LPAR3LPAR2NLRP3ABCC3 | |
| SCHEMBL3702206 | 0.86 | LPAR1 (0.47) | LPAR1LPAR3LPAR2NLRP3ABCC3 | |
| SCHEMBL3705982 | 0.86 | LPAR1 (0.49) | LPAR1LPAR3LPAR2NLRP3ABCC3 | |
| SCHEMBL3705977 | 0.85 | LPAR1 (0.45) | LPAR1LPAR3LPAR2NLRP3ABCC3 | |
| SCHEMBL3702507 | 0.85 | LPAR1 (0.45) | LPAR1LPAR3LPAR2NLRP3ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |