Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710797 | 0.88 | MAPT (0.43) | MDM2MAPTKDM4EMAPK1HTT | |
| SCHEMBL503725 | 0.83 | MAPT (0.48) | L3MBTL1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL503662 | 0.75 | MAPT (0.44) | MDM2L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL3788120 | 0.73 | MAPT (0.36) | MDM2LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL334112 | 0.71 | MAPT (0.61) | LMNAMAPTKDM4EMAPK1HTT | |
| SCHEMBL334113 | 0.71 | MAPT (0.57) | LMNAMAPTKDM4EMAPK1HTT | |
| SCHEMBL503848 | 0.69 | MAPT (0.45) | MDM2MAPTKDM4EMAPK1HTT | |
| SCHEMBL333737 | 0.69 | PPARG (0.45) | MAPTKDM4EMAPK1HTTPKM | |
| SCHEMBL4922512 | 0.69 | SMN1; SMN2 (0.49) | L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL503499 | 0.69 | MDM2 (0.45) | MDM2L3MBTL1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076566-A2 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |