Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707097 | 0.88 | MDM2 (0.41) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL334112 | 0.79 | MAPT (0.61) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL334113 | 0.76 | MAPT (0.57) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL333737 | 0.72 | PPARG (0.45) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL335008 | 0.71 | PTGES (0.49) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL503725 | 0.69 | MAPT (0.48) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL503613 | 0.69 | MAPT (0.48) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL333738 | 0.69 | PPARG (0.48) | KDM4EPTGES | |
| SCHEMBL333957 | 0.68 | MAPT (0.42) | MAPTHSD17B10HTTMAPK1HPGD | |
| SCHEMBL335009 | 0.67 | PTGES (0.52) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076566-A2 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |