Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189183 | 0.91 | PIK3CG (0.53) | PIK3CDPIK3CGPIK3CAITKABL1 | |
| SCHEMBL3710167 | 0.91 | PIK3CG (0.49) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL13188578 | 0.91 | PIK3CG (0.53) | PIK3CDPIK3CGPIK3CAITKABL1 | |
| SCHEMBL13188713 | 0.91 | PIK3CG (0.49) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL3717589 | 0.90 | PTGES (0.53) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL13188220 | 0.89 | PIK3CG (0.48) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL3711584 | 0.89 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL13188292 | 0.88 | PIK3CG (0.53) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL13188400 | 0.88 | PIK3CG (0.67) | PIK3CDPIK3CGPIK3CAABL1 | |
| SCHEMBL13188210 | 0.88 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |