Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 20/20 | 0.71 |
| ▸ | AURKA | O14965 | 19/20 | 0.71 |
| ▸ | AURKB | Q96GD4 | 9/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667095 | 0.93 | RPS6KB1 (0.82) | RPS6KB1AURKAAURKB | |
| SCHEMBL3717337 | 0.90 | RPS6KB1 (0.87) | RPS6KB1AURKAAURKB | |
| SCHEMBL667258 | 0.86 | AURKA (0.87) | RPS6KB1AURKAAURKB | |
| SCHEMBL666799 | 0.86 | RPS6KB1 (0.83) | RPS6KB1AURKAAURKB | |
| SCHEMBL3804003 | 0.83 | AURKA (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL666814 | 0.83 | RPS6KB1 (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL666981 | 0.83 | RPS6KB1 (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL664106 | 0.82 | RPS6KB1 (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL667213 | 0.81 | RPS6KB1 (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL666037 | 0.81 | RPS6KB1 (0.85) | RPS6KB1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396307-A1 | NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES | Merck Patent GmbH (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010093419-A1 | NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2010-08-19 | — | — | WO | disclosed |