SCHEMBL3707670

SCHEMBL3707670

CCOC(=O)c1cnc(-c2ccc3c(c2)c(C#N)cn3C)s1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.52
DBF4 Q9UBU7 1/20 0.52
XDH P47989 5/20 0.43
IMPDH2 P12268 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707802 0.89 CDC7 (0.51) CDC7DBF4XDH
SCHEMBL3704111 0.88 XDH (0.52) CDC7DBF4XDH
SCHEMBL3704109 0.86 XDH (0.55) CDC7DBF4XDH
SCHEMBL3702922 0.86 XDH (0.54) CDC7DBF4XDH
SCHEMBL3707314 0.86 XDH (0.49) CDC7DBF4XDH
SCHEMBL3712121 0.86 XDH (0.46) XDH
SCHEMBL3705167 0.85 XDH (0.55) CDC7DBF4XDH
SCHEMBL3707310 0.82 XDH (0.58) CDC7DBF4XDH
SCHEMBL3705184 0.81 CDC7 (0.43) CDC7DBF4XDH
SCHEMBL3708608 0.79 CDC7 (0.53) CDC7DBF4XDHIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010093191-A2 NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES LTD. (KR) 2010-08-19 WO disclosed