Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342577 | 0.77 | MEN1 (0.33) | HDAC1HDAC2 | |
| SCHEMBL16584643 | 0.77 | MEN1 (0.33) | HDAC1HDAC2 | |
| SCHEMBL24443479 | 0.75 | LMNA (0.40) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL30361364 | 0.74 | NR1H2 (0.39) | L3MBTL1AAK1CYP2D6LMNAMAPK1 | |
| SCHEMBL5131533 | 0.72 | CYP1A2 (0.39) | TDP1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL5131536 | 0.72 | CYP1A2 (0.39) | TDP1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL3632878 | 0.72 | NPY5R (0.41) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL636115 | 0.72 | AAK1 (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL9382586 | 0.72 | SMN1; SMN2 (0.41) | TDP1ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL642839 | 0.72 | SMN1; SMN2 (0.41) | TDP1ALDH1A1TSHRHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |