Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | USP7 | Q93009 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710669 | 0.92 | MEN1 (0.59) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3709204 | 0.88 | MEN1 (0.74) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3715641 | 0.85 | MEN1 (0.73) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3705340 | 0.84 | MEN1 (0.78) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6781299 | 0.82 | MEN1 (0.68) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3704381 | 0.80 | MEN1 (0.70) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3705385 | 0.79 | USP7 (0.79) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3714403 | 0.78 | USP7 (0.69) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3708650 | 0.78 | USP7 (0.69) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3706264 | 0.78 | MEN1 (0.60) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081783-A1 | NOVEL SPECIFIC INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2010-07-22 | — | — | WO | claimed |