Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 17/20 | 0.44 |
| ▸ | AKT2 | P31751 | 17/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3708885 | 0.99 | AKT1 (0.43) | AKT1AKT2CCR1CCR8USP30 | |
| SCHEMBL2979235 | 0.86 | AKT1 (0.43) | AKT1AKT2CCR1CCR8USP30 | |
| SCHEMBL3701974 | 0.78 | AKT1 (0.48) | AKT1AKT2USP30 | |
| SCHEMBL3713327 | 0.78 | USP30 (0.58) | AKT1AKT2USP30 | |
| Hydrochloric Acid SCHEMBL3705458 | 0.77 | USP30 (0.57) | AKT1AKT2USP30 | |
| SCHEMBL13257210 | 0.73 | CCR1 (0.43) | CCR1CCR8METAP2 | |
| SCHEMBL13377809 | 0.73 | CCR1 (0.54) | CCR1CCR8METAP2 | |
| SCHEMBL27823375 | 0.72 | AKT1 (0.44) | AKT1AKT2 | |
| Hydrochloric Acid SCHEMBL3708218 | 0.72 | CCR1 (0.42) | CCR1CCR8METAP2 | |
| SCHEMBL30599933 | 0.72 | CCR1 (0.46) | CCR1CCR8METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396330-B1 | FUSED PYRIMIDINES | BAYER IP GMBH (DE) | 2016-04-06 | — | — | EP | disclosed |
| EP-2396330-A1 | FUSED PYRIMIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091808-A1 | FUSED PYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-19 | — | — | WO | disclosed |