Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711036 | 0.93 | KCNH2 (0.44) | KCNH2HDAC1CYP19A1CNR1CNR2 | |
| SCHEMBL7016894 | 0.91 | KDM5A (0.40) | KCNH2HDAC1CYP19A1ALDH1A1POLB | |
| SCHEMBL27710988 | 0.87 | KCNH2 (0.46) | KCNH2HDAC1CYP19A1CNR1CNR2 | |
| SCHEMBL293555 | 0.86 | KCNH2 (0.36) | KCNH2HDAC1CYP19A1CNR1CNR2 | |
| SCHEMBL8664135 | 0.85 | KCNH2 (0.48) | KCNH2HDAC1CYP19A1CNR1CNR2 | |
| SCHEMBL294176 | 0.84 | KDM5A (0.35) | KCNH2HDAC1CYP19A1CNR1CNR2 | |
| SCHEMBL28063315 | 0.83 | MIF (0.36) | KCNH2HDAC1CYP19A1HRH4HRH3 | |
| SCHEMBL294516 | 0.82 | KDM5A (0.33) | KCNH2HDAC1CYP19A1ALDH1A1POLB | |
| Quinoline SCHEMBL27743469 | 0.82 | ALDH1A1 (0.42) | KCNH2HDAC1CNR1CNR2HTT | |
| SCHEMBL2629293 | 0.81 | KCNH2 (0.47) | KCNH2CYP19A1CNR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113347969-A | Composition for eliminating senescent cells | 维也纳自然资源与生命科学大学 | 2021-09-03 | — | — | CN | claimed |
| CN-111065391-A | Compositions containing conjugates of cannabinoid analogs and methods of use | 维利法姆企业有限责任公司 | 2020-04-24 | — | — | CN | claimed |
| EP-1680116-A1 | COMBINATION TREATMENT OF OBESITY INVOLVING SELECTIVE CB1-ANTAGONISTS AND LIPASE INHIBITORS | Solvay Pharmaceuticals GmbH (DE) | 2006-07-19 | — | — | EP | claimed |
| EP-1200094-B1 | OPHTHALMIC COMPOSITIONS CONTAINING ANTIBIOTICS AND NSAIDS | ALLERGAN INC (US) | 2006-06-21 | — | — | EP | claimed |
| EP-1663215-A1 | NOVEL MEDICAL USE OF SELECTIVE CB1- RECEPTOR ANTAGONISTS | Solvay Pharmaceuticals GmbH (DE) | 2006-06-07 | — | — | EP | claimed |
| US-20050101585-A1 | Use of selective CB1-antagonists in medical treatments | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-05-12 | — | — | US | claimed |
| WO-2005039579-A1 | COMBINATION TREATMENT OF OBESITY INVOLVING SELECTIVE CB1-ANTAGONISTS AND LIPASE INHIBITORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-05-06 | — | — | WO | claimed |
| WO-2005020992-A1 | NOVEL MEDICAL USE OF SELECTIVE CB1-RECEPTOR ANTAGONISTS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-03-10 | — | — | WO | claimed |
| WO-2024125320-A1 | USE OF DIPYRIDAMOLE AND PREPARATION THEREOF IN PREVENTING AND TREATING ATOPIC DERMATITIS | 智泽童康(广州)生物科技有限公司 | 2024-06-20 | — | — | WO | disclosed |
| WO-2024110503-A1 | METHODS FOR TREATING EYETEAR FILM DEFICIENCY | BAUSCH + LOMB IRELAND LIMITED (IE) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024110505-A1 | METHODS FOR TREATING EYETEAR FILM DEFICIENCY | BAUSCH + LOMB IRELAND LIMITED (IE) | 2024-05-30 | — | — | WO | disclosed |
| US-20240165147-A1 | Methods for Treating Eyetear Film Deficiency | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2024-05-23 | — | — | US | disclosed |
| US-20240165019-A1 | Methods for Treating Eyetear Film Deficiency | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2024-05-23 | — | — | US | disclosed |
| US-20240102034-A1 | CANNABIS PLANT WITH INCREASED CANNABIGEROLIC ACID | CANOPY GROWTH CORPORATION (CA) | 2024-03-28 | — | — | US | disclosed |
| WO-1995015315-A1 | 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | disclosed |
| CN-1026695-C | Synthesis of N-tertiary alkyl-1, 2-diacylhydrazines | ROHM & HAAS (US) | 1994-11-23 | — | — | CN | disclosed |
| EP-0248594-B1 | Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same | ORTHO PHARMA CORP (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5164381-A | Cardiovascular, antiinflammatory | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| US-4826868-A | 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0248594-A2 | Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-12-09 | — | — | EP | disclosed |