Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301346 | 0.84 | MAOB (0.54) | MAOBMAOACYP19A1HTR2ATAAR1 | |
| SCHEMBL6682241 | 0.81 | TAAR1 (0.54) | MAOBTAAR1CYP2A6ALDH1A1 | |
| SCHEMBL28390632 | 0.81 | MAOB (0.60) | MAOBMAOACYP19A1HTR2ATAAR1 | |
| SCHEMBL16191225 | 0.81 | HTT (0.51) | MAOBMAOAHTR2ATAAR1CYP2A6 | |
| SCHEMBL30963236 | 0.79 | TSHR (0.54) | MAOBMAOASMN1; SMN2ALDH1A1FFAR4 | |
| SCHEMBL30963244 | 0.79 | TSHR (0.54) | MAOBMAOASMN1; SMN2ALDH1A1FFAR4 | |
| SCHEMBL23413337 | 0.78 | ALDH1A1 (0.46) | MAOAHTR2ATAAR1CYP2A6ALDH1A1 | |
| SCHEMBL12021475 | 0.78 | KDM4E (0.47) | TAAR1ALDH1A1 | |
| SCHEMBL20226499 | 0.78 | SKP2 (0.48) | TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20226583 | 0.77 | ALDH1A1 (0.42) | CYP19A1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |