Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712291 | 0.89 | XDH (0.41) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3707254 | 0.86 | CDC7 (0.41) | CDC7DBF4PDE5AEGFRKDR | |
| SCHEMBL3714706 | 0.85 | CDC7 (0.39) | CDC7DBF4PDE5AEGFRKDR | |
| SCHEMBL3708893 | 0.80 | CDC7 (0.44) | CDC7DBF4PDE5ADHODHTRPM8 | |
| Hydrochloric Acid SCHEMBL3708891 | 0.80 | CDC7 (0.44) | CDC7DBF4PDE5ADHODHTRPM8 | |
| SCHEMBL3707471 | 0.78 | CDC7 (0.45) | CDC7DBF4DHODHTRPM8ALDH1A1 | |
| SCHEMBL3710384 | 0.77 | CDC7 (0.48) | CDC7DBF4DHODHTRPM8ALDH1A1 | |
| SCHEMBL3714669 | 0.75 | XDH (0.40) | ALDH1A1KDM4EPOLBSMN1; SMN2NPC1 | |
| SCHEMBL3707628 | 0.74 | XDH (0.39) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL8867336 | 0.71 | CDC7 (0.62) | CDC7DBF4DHODHTRPM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |