Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 12/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709889 | 0.90 | GPR119 (0.45) | GPR119HRH1KCNH2 | |
| SCHEMBL3651433 | 0.90 | HRH1 (0.44) | GPR119HRH1KCNH2 | |
| SCHEMBL3648875 | 0.90 | HRH1 (0.46) | GPR119HRH1KCNH2 | |
| SCHEMBL3711292 | 0.89 | HRH1 (0.51) | HRH1KCNH2 | |
| SCHEMBL3718501 | 0.86 | HRH1 (0.51) | HRH1KCNH2 | |
| SCHEMBL3715446 | 0.86 | HRH1 (0.47) | HRH1KCNH2 | |
| SCHEMBL3716534 | 0.86 | HRH1 (0.45) | HRH1KCNH2 | |
| SCHEMBL3645139 | 0.86 | HRH1 (0.62) | HRH1KCNH2 | |
| SCHEMBL3647335 | 0.85 | HRH1 (0.59) | HRH1KCNH2 | |
| SCHEMBL3657078 | 0.84 | HRH1 (0.59) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |