Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3707739 | 0.99 | MAPT (0.60) | MAPTMEN1ALDH1A1KMT2AACHE | |
| SCHEMBL3711300 | 0.86 | MAPT (0.70) | MAPTMEN1ALDH1A1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL3706215 | 0.85 | MAPT (0.68) | MAPTMEN1ALDH1A1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL3703905 | 0.80 | MEN1 (0.61) | MAPTMEN1ALDH1A1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL3708908 | 0.80 | MAPT (0.81) | MAPTACHENPSR1HTR1ADRD2 | |
| SCHEMBL3713046 | 0.78 | MAPT (0.59) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3705133 | 0.78 | MAPT (0.58) | MAPTMEN1ALDH1A1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL3708818 | 0.78 | MAPT (0.58) | MAPTALDH1A1HTR1A | |
| SCHEMBL3715364 | 0.77 | MAPT (1.00) | MAPTALDH1A1ACHENPSR1CCR3 | |
| SCHEMBL27429046 | 0.76 | MAPT (0.74) | MAPTACHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |